In this paper two theoretical models have been considered for the prediction of path loss for two different districts in Mosul city, using MATLAB 7.4 program. The Walfisch-Ikegami (W-I) model for uniform heights and similar buildings in the Karama district . The other model is Okumura-Hata (OH) model applied for irregular and dissimilar buildings in the Almajmoa'a district. The information buildings heights are obtained from the civil Eng. Depart. in Mosul university. In this paper it can be shown that The effect of distance in regular area (karama) on path loss is about 10 dB larger than irregular area (Almajmoa'a), and The effect of varying antenna height in regular area (karama) on path loss is about 7 dB greater than irregular area (Almajmoa'a) for 40 meter variation.